vegansaurus!

05/13/2014

Male scientists stress out otherwise super-chill lab rats, or Why animal testing is the wackness  »

From Flickr user Feistea.

New findings show that male scientists may cause stress to rats and mice, resulting in different test results than female scientists achieve (warning: I don’t know the full extent of shiz they are doing to these poor animals but they seem to know a lot about their pain threshold): 

In research published online April 28 in Nature Methods, the scientists report that the presence of male experimenters produced a stress response in mice and rats  equivalent to that caused by restraining the rodents for 15 minutes in a tube or forcing them to swim for three minutes. This stress-induced reaction made mice and rats of both sexes less sensitive to pain. Female experimenters produced no such effects.

And it’s not just pain (shudder! Ugh, why do they know so much about what causes them pain!), “the researchers found that other behavioural assays sensitive to stress were affected by male but not female experimenters or T-shirts.”

There’s “good news” though!

The problem is easily solved by simple changes to experimental procedures. For example, since the effect of males’ presence diminishes over time, the male experimenter can stay in the room with the animals before starting testing.  At the very least, published papers should state the gender of the experimenter who performed the behavioral testing.

Hmm. I can think of a better solution. How about we not test on animals at all?! Yay!

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From flickr user Halfabear.

But seriously, animal testing is so flawed. First of all, I doubt these mice and rats aren’t generally stressed. So maybe they are going through these tests with super pain-resilience all the time. But that’s just one of a plethora of issues. Take a look at what one writer for the Guardian had to say:

I analysed in detail 27 systematic reviews examining the contributions of animal experiments to human healthcare. Their outcomes are remarkably consistent. Animal studies rarely contribute to the development of clinical interventions effective in human patients.

It’s not hard to fathom why. Animals have a plethora of genetic, biochemical and physiological differences that alter disease progression, drug uptake, distribution and effect. Stressful environments and experiments are common, and distort outcomes. Additionally, numerous studies have revealed scientific flaws in the design of many animal experiments.

The moral of the story: ANIMALS AREN’T PEOPLE. They respond to treatments and experiments differently! And while some studies may save human lives, check this out: 

Modern drugs are more carefully studied than ever before. After lengthy tests on animals, those considered safe, and potentially effective, enter very limited human trials. About 92% are then weeded out and deemed unsafe or ineffective.

The remaining 8% are some of the most closely scrutinised compounds on the planet. You might be forgiven, therefore, for assuming they are safe. But at least 39 studies over three decades have ranked adverse drug reactions as an important cause of hospital deaths. Only heart disease, cancer and stroke are more reliably lethal.

Slate chimes in too: 

just how often do animal tests predict side effects in humans? Surprisingly, although it is central to the legitimacy of animal testing, only a dozen or so scholars over the past 30 years have explored this question. The results, such as they are, have been somewhat discouraging. One of the scientists, Ralph Heywood, stated in 1989 that “there is no reliable way of predicting what type of toxicity will develop in different species to the same compound.” The concordance between man and animal toxicity tests, he said, assessing three decades of studies on the subject, was somewhere below 25 percent. “Toxicology,” concluded Heywood, “is a science without a scientific underpinning.”

Dude. If the main argument is that animal testing saves human lives, I say we have a problem. I can go on—or rather PCRM can—but the point is, animal testing is not the great life-saving necessary evil it’s painted to be.

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Fun with false dichotomies. 

But whether it saves human lives or not, the bottom line is it’s just not ethical. To be honest, I do care more about people than animals. If I could only save a human baby or a puppy—in some bizarre world where I ever actually have to make this choice—I would pick the baby. I’m not totally sure why but I think I would. BUT just because I value humans more than animals, I don’t think that means we can just do whatever we want to animals. Feel free to correct my reasoning but the way I think about it is like how I, without a doubt, care more about my sister than your sister. If one of them had to die, I would rather it was your sister. Truthbomb. But I don’t think that means we should go doing experiments on your sister because it might save my sister’s life! 

Thinking that another being is lesser and therefore you can do with them what you will is exactly why people did horrible experiments on jewish captives in nazi Germany or people of color in America. It’s just wrong. 

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